Jakub Štofila

Percutaneous endoscopic techniques and their position in diagnostic and treatment process focused on vertebrogenic diseases: epiduroscopy and endoscopic discectomy

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Percutaneous endoscopic techniques are modern minimally-invasive methods that enable effective treatment of pain and accompanying neurological symptoms in patients with an intervertebral disc herniation and/or other epidural pathologies. Available evidence supports their efficacy and safety therefore, they deserve a stable position in addressing specific types of spinal pathologies. Epiduroscopy is a suitable diagnostic and therapeutic … Read more

Oxidative Stress and Opioids

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In recent years, research has shown the involvement of free radicals in the development of the pain that accompanies many pathological conditions. In the treatment of acute and chronic pain, the most effective therapies are natural and synthetic opioid alkaloids. Their metabolism in itself may contribute to the formation of free radicals and thus affect … Read more

Cervicobrachial syndrome in conjunction with osteomyelitis in the forearm

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Upper limb pain is one of the most common manifestations of pain. The origin can vary widely and can be the result of several aetiologies. In this work, we present a case of a patient with cervicobrachial syndrome who overlapped with another nosology unit. Despite the treatment provided, worsening and unrelenting pain in the right … Read more

Plasma antioxidant status in patients undergoing long-term opioid treatment

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Opioid treatment is now an integral part of pharmacotherapy for severe chronic malignant and non-malignant pain. Currently, there is a sufficient selection of opioids to allow individualized pain treatment. Several experimental studies have confirmed the effect of opioids on oxidative stress. The aim of this work is to determine the presence of redox changes occurring … Read more

Neuromodulation techniques in the management of vertebrogenic pain syndromes

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Neuromodulation techniques represent a spectrum of therapeutic approaches with various options to influence the pain path-ways. It can be either the application of the chosen medication or the action of electrical signals in the vicinity of the peripheral (PNS) or central nervous system (CNS), by which the perception of pain is modulated. The application of … Read more

A multidisciplinary approach in the diagnostics of vertebrogenic diseases from neurologist’s and physio-rehabilitation specialist’s perspective

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Back pain includes a big variety of diseases and clinical symptoms. They are the most common cause of pain and disability in the recent human population. The strategy of diagnstics and treatment is often ill-conceived. The aim of this paper is to inform about the options of multidisciplinary diagnostics by a neurologist, physiotherapist, pain management … Read more

A multidisciplinary approach in the diagnostics of vertebrogenic diseases from a radiologist’s and interventional pain management specialist’s perspective

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Back pain includes a big variety of diseases and clinical symptoms. They are the most common cause of pain and disability in the recent human population. The strategy of diagnstics and treatment is often ill-conceived. The aim of this paper is to inform about the options of multidisciplinary diagnostics by a neurologist, physiotherapist, pain management … Read more

A multidisciplinary approach in the diagnostics of vertebrogenic diseases from a radiologist’s and inverventional pain management specialist’s perspective

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Back pain includes a big variety of diseases and clinical symptoms. They are the most common cause of pain and disability in the recent human population. The strategy of diagnstics and treatment is often ill-conceived. The aim of this paper is to inform about the options of multidisciplinary diagnostics by a neurologist, physiotherapist, pain management … Read more

COMPLEX THERAPY OF LUMBAR RADICULAR SYNDROME (OVERVIEW OF THERAPEUTIC POSSIBILITIES)

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Back pain is becoming a huge socio-economic social problem. In addition to treatment costs, long-term disability of patients is also a problem, and economic losses at family level and, ultimately, in society. Radicular pain is most often caused by herniation of the intervertebral disc. Pain running predominantly from the lumbo-sacral back of the spine area … Read more

Radiofrequency denervation and cryoablation of the lumbar zygapophysial joints in the treatment of positive lumbar facet joint syndrome

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A report of three cases Radiofrequency denervation of the zygapophysial (facet) joints is a frequently performed procedure for chronic low back pain. However, cryoablation represents a novel therapeutic approachforthiscondition. Weobserved and analyzed 3cases with confirmed positive lumbar facet joint syndrome. Our results show a significant improvement in the clinical state of the patients in the … Read more

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